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ORIGINAL ARTICLE
Year : 2021  |  Volume : 5  |  Issue : 2  |  Page : 145-148

Studies on antistress activity of Curculigo Orchioides gaertn


1 Drugs Testing Laboratory Avam Anusadhan Kendra, Raipur, Chhattisgarh, India
2 Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India
3 Department of Balroga, Shri N P A Government Ayurved College, Raipur, Chhattisgarh, India

Correspondence Address:
Nagendra Singh Chauhan
Drugs Testing Laboratory Avam Anusadhan Kendra, 1st Floor, Government Ayurvedic Hospital Building, Government Ayurvedic College Campus, G.E. Road, Raipur - 492 010, Chhattisgarh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bbrj.bbrj_12_21

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The aim of this study was to evaluate the antistress activity of rhizomes ethanolic extract of Curculigo orchioides Gaertn in vivo, using mice with stress-induced injury. The effect of Curculigo orchioides on motor coordination, spontaneous locomotor activity, immobility time, and analgesia was evaluated in mice using standard procedure. The ethanolic extract of Curculigo orchioides at dose levels, i.e., 100 and 200 mg/kg shows pronounced antistress activity evidenced by reduced immobility time in forced swimming and tail test. It also improved motor coordination and enhanced analgesic effect compared to standard diazepam. The Curculigo orchioides was found to be a antistress activity.


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