Biomedical and Biotechnology Research Journal (BBRJ)

REVIEW ARTICLE
Year
: 2020  |  Volume : 4  |  Issue : 4  |  Page : 302--304

FNCas9 editor-linked uniform detection assay: An innovative COVID-19 sleuth


Tarun Kumar Suvvari, MD Nawaz, Mani Kruthika Mantha 
 Rangaraya Medical College, Kakinada, Andhra Pradesh, India

Correspondence Address:
Mr. Tarun Kumar Suvvari
Rangaraya Medical College, Kakinada, Andhra Pradesh
India

Relying on traditional diagnostic approaches like quantitative polymerase chain reaction is not appropriate for both time and cost in sudden outbreaks and pandemics such as COVID-19. In such cases, diagnostic approaches through rapid sequencing of pathogenic DNA and RNA are important for accelerated clinical prognosis. FNCas9 Editor-Linked Uniform Detection Assay (FELUDA) is one such diagnostic approach toward the pathogenic genome, developed by CSIR-IGIB. FELUDA is a paper strip diagnostic test like pregnancy, based on clustered regularly interspaced short palindromic repeats/Cas technology of gene editing. FELUDA showed 96% sensitivity and 98% specificity across all range of viral loads in clinical samples. Due to its low cost, it can drastically reduce the Indian budget toward the rapid testing and COVID-19 diagnostic kits.


How to cite this article:
Suvvari TK, Nawaz M D, Mantha MK. FNCas9 editor-linked uniform detection assay: An innovative COVID-19 sleuth.Biomed Biotechnol Res J 2020;4:302-304


How to cite this URL:
Suvvari TK, Nawaz M D, Mantha MK. FNCas9 editor-linked uniform detection assay: An innovative COVID-19 sleuth. Biomed Biotechnol Res J [serial online] 2020 [cited 2022 Jan 23 ];4:302-304
Available from: https://www.bmbtrj.org/article.asp?issn=2588-9834;year=2020;volume=4;issue=4;spage=302;epage=304;aulast=Suvvari;type=0