Close
  Indian J Med Microbiol
 

Figure 1: (a) Differential scanning fluorimetry plots of a Mycobacterium tuberculosis glutamate racemase native, with D-glutamate and lead 1. (b) The plot of derivative fluorescent-based signal against temperature; Tm and ΔTm (shift) can be measured from the minimum of the plot. (c) Structure of identified lead 1 with Tm and IC50 value in Bsb

Figure 1: (a) Differential scanning fluorimetry plots of a <i>Mycobacterium tuberculosis</i> glutamate racemase native, with D-glutamate and lead 1. (b) The plot of derivative fluorescent-based signal against temperature; <i>T</i><sub>m</sub> and Δ<i>T</i><sub>m</sub> (shift) can be measured from the minimum of the plot. (c) Structure of identified lead 1 with <i>T</i><sub>m</sub> and IC<sub>50</sub> value in <i>Bsb</i>