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  Indian J Med Microbiol
 

Figure 1: Model of viral transmission through viral “biofilms,” including (i) viral biofilm formation at the surface of infected cells, (ii) transfer of these infectious adhesive structures through dynamic interactions between infected and uninfected cells (permissive or nonpermissive cells). The rupture and adhesion of biofilm fragments to the surface of these cells might lead to both the direct infection of permissive target cells (iii) and/or the indirect infection through contacts with other cells (e.g., dendritic cells or nonpermissive cells) that might capture viral biofilms on their cell surface (iv), and transfer them to target permissive cells (v) (”transinfection”)[2]

Figure 1: Model of viral transmission through viral “biofilms,” including (i) viral biofilm formation at the surface of infected cells, (ii) transfer of these infectious adhesive structures through dynamic interactions between infected and uninfected cells (permissive or nonpermissive cells). The rupture and adhesion of biofilm fragments to the surface of these cells might lead to both the direct infection of permissive target cells (iii) and/or the indirect infection through contacts with other cells (e.g., dendritic cells or nonpermissive cells) that might capture viral biofilms on their cell surface (iv), and transfer them to target permissive cells (v) (”transinfection”)<sup>[2]</sup>